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07.10.2021 |

On-target effects of genome editing techniques: (Un)repaired DNA damage, a hindrance to safety and development?

GeneWatch UK, September 2021

Genome editing encompasses new forms of genetic engineering techniques being increasingly applied to the development of agricultural and biomedical technologies, by ‘editing’ the DNA of living organisms (i.e. their ‘genome’), including plants, animals and human cells. The genome editing process involves the use of biological molecules (enzymes) which cut the DNA and various mechanisms which then repair it. Arguments over the safety and efficacy of genome editing techniques at the molecular level often hinge on aspects of their ‘precision’ in targeting DNA sequences of interest, and the ‘indistinguishability’ of engineered traits from mutations that may arise naturally.

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