GMO news related to the United States

13.11.2019 |

New campaign highlights threats of gene editing

Protect Nature Now explains the issues in simple terms and suggests ways to spread the word

At GMWatch, we're concerned that vast numbers of people are still unaware of the threats posed by new gene-editing techniques. Now a new campaign and set of learning and sharing tools have made it easy to understand the issues and spread the word to friends and contacts.

The campaign, called Protect Nature Now, is a project of The Institute for Responsible Technology. Protect Nature Now has released a short video, The New Global Threat from GMOs, which explains the issues in simple terms. The dangers go way beyond food, encompassing human and animal health, animal welfare, the integrity of our soils, and entire ecosystems.

16.10.2019 |

Gene Editing Mishaps Highlight Need for FDA Oversight

A Midwestern company’s quest to genetically engineer the world’s first hornless dairy cows hit a snag this summer when the U.S. Food and Drug Administration found extra genes in the cows that weren’t supposed to be there. The mistakes that FDA caught – but the company missed – highlight the importance of government oversight of gene-edited foods at a time when industry groups are pushing for deregulation.

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Latham, a biologist and former genetic engineer, also points to recent findings from Japan that he believes may be more consequential than the FDA’s findings, and have greater implications for the regulatory landscape. In a 2019 study, Japanese researchers reported that edited mouse genomes had acquired DNA from the E. coli genome, as well as goat and bovine DNA. This stray DNA came from the gene editing reagents, the delivery method used to make the edits.

The findings, Latham wrote in Independent Science News, “are very simple: cutting DNA inside cells, regardless of the precise type of gene editing, predisposes genomes to acquire unwanted DNA.” He said these findings “imply, at the very least, the need for strong measures to prevent contamination by stray DNA, along with thorough scrutiny of gene-edited cells and gene-edited organisms. And, as the Recombinetics case suggests, these are needs that developers themselves may not meet.”

15.10.2019 |

Let them eat GM cottonseed!

Potentially dangerous new GMO gains US FDA approval to be fed to humans and animals – poor and hungry targeted. Report: Claire Robinson

US FDA (Food and Drug Administration) regulators have approved a new type of GM cotton, the seed of which is to be used for human and animal consumption. The cotton, developed by researchers at Texas A&M University, is being touted as a protein-rich way to feed the poor and hungry. However, the many risks of this GM food are being ignored.

The GM cotton is engineered to have lower than normal levels of a substance called gossypol in the seed, but normal levels in other parts of the plant. Gossypol is useful to the plant for resisting pests and diseases, but it is toxic for humans and animals (though less so to mature ruminants such as cows) to eat.

09.10.2019 |

United States - The precautionary principle to deal with GM animals?

In the United States, draft guidelines, put on the table by the Food and Drugs Agency (FDA), plans to regulate any animal whose genome has been modified. The approach chosen embraces almost all modern biotechnologies of genetic modification, beyond the only techniques inserting exogenous DNA. A draft discontenting the pro-GMOs. The application that may be required to obtain a commercial authorization partly meets the dreams of the european opponents to GMOs …

09.10.2019 |

A New Bill Could Help Protect the Sacred Seeds of Indigenous People

Clayton Brascoupé has farmed in the red-brown foothills of New Mexico’s Sangre de Cristo Mountains for more than 45 years. A Mohawk-Anishnaabe originally from a New York reservation, Brascoupé married into the Pueblo of Tesuque tribe and has since planted at least 60 varieties of corns, beans, squashes, and other heirloom crops grown for millennia by the area’s Native Americans.

For more than three decades, he has taught other indigenous farmers about sustainable agricultural practices, seed saving, healthy eating, and traditional food production. With seed diversity loss a grave concern in recent years, Brascoupé has been cataloguing the seeds stored by his own family. But earlier this spring, two of his tool sheds burned down, destroying several dozen varieties.

“I will have trouble replacing them. They may be lost for good,” said Brascoupé, who runs the Traditional Native American Farmers Association.

17.09.2019 |

Gene-edited animals will intensify factory farming and the climate crisis, could harm human health

New report highlights urgent need for safety assessments, oversight


WASHINGTON — A new report from Friends of the Earth and Logos Environmental reveals that the use of gene editing in farm animals poses risks to human health, the environment and animal welfare. The report comes on the heels of research by the FDA showing that gene-edited hornless cattle have unexpected antibiotic resistant genes, despite researchers’ original claims that they did not contain any genetic errors. This new report sheds light on the unintended consequences of gene editing and considers the implications for U.S. regulations.

Many genetically engineered farm animals are currently in development, funded by private companies or governments and enabled by new gene editing technologies such as CRISPR. Examples include super-muscly cows and pigs, hornless cattle, chickens and pigs made to resist certain diseases, cows with human genes, and other genetic experiments. Production of these gene-edited farm animals is often done with little public awareness or input.

14.09.2019 |

Monsanto’s Spies

The agri-chemical giant has a storied history of using shady tactics to attack critics and influence the media.

It was early March when other reporters first noticed Sylvie Barak. About a half a dozen journalists were in a northern California courtroom to cover a third lawsuit alleging that Monsanto’s pesticide glyphosate causes cancer.

Barak told others that she was a freelancer for the BBC. She was friendly and helpful, listened earnestly as reporters discussed their private lives; she offered parenting tips and shared her thoughts on the trial.

12.08.2019 |

FDA Finds Unexpected Antibiotic Resistance Genes in 'Gene-Edited' Dehorned Cattle

By Jonathan Latham, PhD and Allison Wilson, PhD

Gene-editing is seen by many as the ultimate in precision breeding. Polled cattle, whose horns have been genetically removed, have been presented as exemplars of this–a socially beneficial use of precise genome engineering. Such hornless cattle were produced in 2016 by Recombinetics, Inc., of St. Paul, Minnesota, a development that was reported in the journal Nature Biotechnology (Carlson et al, 2016).

In that publication, Recombinetics researchers reported detecting no unexpected alterations, such as insertions or deletions of DNA, as a result of the gene-editing procedure. They concluded “our animals are free of off-target events” (Carlson et al, 2016).

09.08.2019 |

Gene-edited hornless cattle: Flaws in the genome overlooked

New techniques for genetic engineering are not as precise as claimed

Cattle are being genetically engineered using gene-editing tools to not grow horns. But according to newly published research by experts at the US Food and Drug Administration (FDA), gene-editing errors in the genome of these cattle are often being overlooked (see abstract below).

The animals were genetically engineered by the biotech company Recombinetics. The company also filed a patent on the genetically engineered cattle. The cattle have for some years been hyped as a positive application of new genetic engineering techniques and a boon for animal welfare, since these GM cattle will not need to be de-horned. However, it appears to have so far gone unnoticed that the gene-editing has resulted in major unintended outcomes.

Unintended effects

The gene editing scissors (nucleases) used in this case are known as TALENs, a method frequently described as highly precise, and indeed, no off-target genetic changes were detected by the developers of these hornless cattle at Recombinetics.

06.08.2019 |

The ethical landscape of gene drive research

Abstract

Gene drive technology has immense potential. The ability to bypass the laws of Mendelian inheritance and almost ensure the transmission of specific genetic material to future generations creates boundless possibilities. But alongside these boundless possibilities are major social and ethical issues. This article aims to introduce gene drive technology, some of its potential applications, and some of the social and ethical issues that arise during research into the technology. For example, is investigation into gene drives hubristic? Would applications of gene drives count as technological fixes? Or does research into such a technology sit on a slippery slope or lock us in to its full‐scale use? Are there perverse effects of engaging in research, and, most importantly, who ought to be included in the decision‐making process regarding research and field trials? Understanding the basic ethical landscape of this technology will prove invaluable to the public, scientists, and policy‐makers as research moves forward.

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